Depression is a mood disorder characterized by feelings of sadness, hopelessness, worthlessness, guilt, anger, fatigue, trouble sleeping, and loss of interest in daily activities. It affects approximately 15 million Americans each year.
Norepinephrine/Dopamine Reuptake Inhibitor (NDRI)
There are several different classes of antidepressants, with varying mechanisms of action. One class of antidepressant drugs works by inhibiting the reuptake of norepinephrine and dopamine into nerve cells. This helps to restore levels of these neurotransmitters in the brain.
Another type of antidepressant drug works by increasing the activity of certain chemicals called serotonin. Serotonin is one of the main neurotransmitters involved in mood regulation. It also plays an important role in regulating sleep patterns.
SSRIs (selective serotonin reuptake inhibitors) are the most commonly prescribed antidepressants. They work by blocking the reabsorption of serotonin back into the nerve cell where it was released. This allows more serotonin to remain in the synapse between neurons, leading to increased levels of serotonin in the brain.
Serotonin & Noradrenaline Reuptake Inhibiting Agent (SNRI)
A serotonin reuptake inhibitor (SSRI) works by increasing the levels of serotonin in the brain. This helps to reduce symptoms of depression. SSRIs also help with sleep issues associated with depression.
Other Types of Antidepressants
There are other types of antidepressants that are used to treat anxiety disorders as well. These include tricyclic antidepressants, monoamine oxidase inhibitors, and atypical antipsychotics.
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